The Chromoprobe Multiprobe® System is an extension of Cytocell's proprietary Chromoprobe® technology whereby DNA FISH probes are reversibly bound to the surface of a glass device. The probes attached to the glass device dissolve back into solution once in contact with hybridisation buffer, whilst denaturation of the probes and target DNA occurs simultaneously under the device once heated. This approach both simplifies the whole FISH procedure and renders it safer and quicker to use.
This system allows multiple FISH probes to be hybridised on the same slide in a spatially separated manner allowing rapid screening of a patient sample for a number of DNA sequences in a single FISH analysis. The assay is supplied in a kit format of 2, 5 or 10 tests and includes hybridisation solution, counterstain, template slides, a hybridisation chamber and full instructions for use. The kit even contains a unique liquid crystal display slide surface thermometer for accurate measurement of the temperature of the denaturation surface.