pA-TN5 transposase

pA-Tn5 transposase is a fusion protein of hyperactive Tn5 transposase and protein A developed for the CUT&Tag assay. For convenience, the fusion protein is pre-loaded with sequencing adapters.

• High enrichment and specificity of the signal around the transcription start site
• No contamination with E. coli DNA
• Flexible versions: loaded or unloaded and excellent for CUT&Tag assays

As it is crucial to target only the protein of interest, a highly specific antibody is critical for the success of the CUT&Tag assay. All Diagenode ChIP-seq grade antibodies are validated for specificity using strict validation criteria.