Advanced 3D cell culture

LunaX Linker™

LunaX Linker™ is an advanced visible‑light crosslinking system engineered for rapid, safe and tunable photopolymerization of Gelomics’ LunaX™ extracellular matrices in standard 24‑, 48‑ and 96‑well plate formats. Powered by dedicated cytoLED™ technology, it delivers narrow‑spectrum 405 nm illumination that activates visible light‑sensitive photoinitiators while minimizing cellular stress and DNA damage typically associated with UV‑based systems. This ensures high cell viability and makes LunaX Linker™ particularly well‑suited for long‑term 3D spheroid, organoid and co‑culture studies.

The system provides fast, uniform crosslinking across multi‑well plates, enabling precise control over matrix stiffness simply by adjusting exposure time, so researchers can closely mimic a wide range of healthy and diseased tissue environments for more physiologically relevant models. Its compact, bench‑top design and intuitive interface integrate seamlessly into existing in vitro workflows, from low‑ to high‑throughput screening, and are fully compatible with the LunaX™ Matrix portfolio and visible‑light photoinitiators. Together, these features make LunaX Linker™ a powerful platform for robust, reproducible 3D cell culture in drug discovery, oncology, immuno‑oncology and tissue engineering applications.

LunaX™ and Gelatin Methacryloyl (GelMA) products

LunaX™ is an ultrapure, photocrosslinkable extracellular matrix (ECM) based on GelMA, with ultra-low endotoxin levels (<10 EU/g). This purity is particularly important for sensitive applications such as macrophage studies, immuno-oncology models, and translational research, where immune activation must be tightly controlled.

LunaX™ stands out for its high bioactivity, supporting cell attachment, proliferation, and proteolytic degradation, which promotes physiologically relevant cell behavior. The hydrogel is optically transparent, facilitating imaging and bioassays, and its tunable stiffness (from 0 up to 25 kPa) allows researchers to mimic a wide range of tissue environments.

The ready-to-use format and reproducibility of LunaX™ provide a reliable platform for disease modeling, drug screening, and tissue engineering, offering a level of control and consistency that is superior to many competing ECM products. By offering an ethical alternative to traditional animal-derived matrices, LunaX™ reduces variability and addresses ethical concerns associated with animal-based products.