Thermo Scientific

NanoDrop microvolume spectrophotometers

Thermo Scientific NanoDrop instruments were the first micro volume UV-Vis spectrophotometers designed specifically for the life science market and have fundamentally changed DNA, RNA and protein analysis. With more than 35000 instruments in laboratories worldwide, NanoDrop instruments have become the recognized standard for micro volume instrumentation.


Compare NanoDrop instruments

 NanoDrop Ultra/UltraC/Ultra FL/UltraC FL
UV-Vis
Fluorescence (selected models)
NanoDrop Eight
UV-Vis
NanoDrop Lite Plus
UV
Product summaryFull-spectrum microvolume UV-Vis measurements with additional options to measure fluorescence, use a standard cuvette, and/or measure highly concentrated samples more accurately with the Acclaro Pro software.High-throughput, full-spectrum microvolume UV-Vis measurementsBasic microvolume UV measurements
Sampling optionsPedestal (All Models)
Cuvette (NanoDrop UltraC and NanoDrop UltraC FL)
PedestalPedestal
Measures 1–2 µL sampleYesYesYes
Dynamic range
(ng/µL dsDNA)
1.0–27,500* ng/µL for dsDNA2,0 - 10000 ng/µL for dsDNA2 - 1500 ng/µL for dsDNA
Full-spectra dataYesYes-
Pre-programmed methods for nucleic acids and proteinsYesYesYes
Measures nucleic acid A260YesYesYes
Measures nucleic acid A260/A280 ratioYesYesYes
Measures nucleic acid A260/A230 ratioYesYesYes
Measures purified protein A280YesYesYes
Measures protein and peptides at A205YesYes-
Measures protein A260/A280 ratioYesYesYes
Pre-programmed methods for colorimetric assays (BCA, Bradford, Lowry, Pierce 660)YesYes-
Custom methodsYesYes-
Built-in cuvette optionYes 
(NanoDrop UltraC and NanoDrop UltraC FL)
--
Standalone local controlYesRequires computerYes
High-resolution touchscreen interfaceYes-Yes
Measures fluorescent-labeled nucleic acid and protein samples using absorbanceYesYes-
Compatible with the NanoDrop Ultra dsDNA and RNA Fluoresence AssaysYes
(NanoDrop UltraFL and NanoDrop UltraC FL)
  
Capable of taking fluorescence measurementsYes
(NanoDrop UltraFL and NanoDrop UltraC FL)
  
Autoblank and AutomeasureYesYes-
Acclaro contaminant identificationYesYes-
21 CFR Part 11 regulatory complianceOptional SciVault 2 SoftwareOptional SciVault 2 Software 
Password-protected accessOptional SciVault 2 SoftwareOptional SciVault 2 Software 
Embedded technical support **YesYes 
Enhanced connectivity (Wi-Fi and Bluetooth™)Yes  
Enhanced connectivity (Wi-Fi and Bluetooth™)Yes   
Cloud CompatibilityYes (Microsoft OneDrive, Google Drive, Thermo Fisher Connect)  
LIMS API SupportYes  

*Lowest detection limit is 0.2 ng/µL with 10 mm cuvette.
**Instrument is delivered with English software and help. Language packs can be downloaded from our website 

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