Diagenode

Shearing technologies

Shearing instruments for successful sample preparation

We provide several types of shearing devices to precisely meet the requirements of your application:

Bioruptor models:

Bioruptor Pico®

Bioruptor Plus®

One®

Megaruptor models:

Megaruptor 3®

Megaruptor 2®


COMPARISON TABLE:

ModelBioruptor Pico®Bioruptor Plus®One®Megaruptor 3®Megaruptor 2®
DescriptionBest suited for ChIP-seq and NGS sample preparationBest suited for cell and tissue sample preparationThe compact bench top device for optimal sample preparationShearing device for long read sequencing applicationsShearing device for long read sequencing applications
Key applications
  • Chromatin shearing 200 bp - 1kb
  • DNA shearing 150 bp - 1 kb
  • RNA shearing 200 bp - 1 kb
  • FFPE nucleic acid extraction
  • Cell lysis and tissue disruption
  • Mass spectrometry
  • Protein aggregation
  • Chromatin shearing 200 bp - 1 kb
  • DNA/RNA/Protein extraction
  • Mass spectrometry
  • Chemical applications
  • Chromatin shearing 200 bp - 1 kb
  • DNA shearing 200 bp - 1 kb
  
Shearing range   From 5 to 100 kb         From 3 to 75 kb         
DNA input   Up to 75 µgUp to 20 µg
Throughput16 samples (for 0.2 ml tube holder)
12 samples (for 0.65 ml tube holder)
6 samples (for 1.5 ml tube holder)
6 samples (for 15 ml tube holder)         
12 samples (for 0.5 ml tube holder)
6 samples (for 1.5 ml tube holder)
6 samples (for 15 ml tube holder)
3 samples (for 50 ml tube holder) 
1 sample         1 – 8 samples in parallel1 – 2 samples in series
Recommended volumes20 - 100 µl (0.2 ml Bioruptor tubes)
100 µl (0.65 ml Bioruptor tubes)
100 - 300 µl (1.5 ml Bioruptor tubes)
300 µl - 2 ml (15 ml Bioruptor tubes)
100 µl (0.5 ml Bioruptor tubes)
100 - 300 µl (1.5 ml Bioruptor tubes)
300 µl - 2 ml (15 ml Bioruptor tubes)
2 - 20 ml (50 ml tubes) 
20 µl and 50 µl         65 – 500 µl         50 – 400 µl         
Temperature controlledyesyesyes  

Reach out for a quotation or more information!

Gitika Emberland

Product specialist

gitika@bionordika.no

Gitika Emberland

 

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