Glycobiology and lectins
Glycobiology is a growing field of research that explores the role of glycan modifications in a variety of areas, from tumor biology to drug discovery. A key to unlocking these deeper insights is lectins. Lectins are a broad class of glycan binding proteins that have their origin as plant proteins known to agglutinate red blood cells. Since Lectins bind glycoconjugates in a manner similar to antigen-antibody interactions, researchers can use them to explore a wide range of biological structures and processes.
We offer products like unconjugated and conjugated lectins, lectin screening kits, lectin antibodies and eluting solutions.
Here is just a selection, for a complete overview visit our webshop.
Glysite™ explorer in situ PLA glycan detection kit and Glysite™ explorer lectins
This kit is a fully integrated tool for the spatial detection of glycans proximal to a protein of interest in FFPE tissues, FFPE cell pellets, and fixed cells. This system integrates a curated panel of Vector’s Glysite™ Explorer Lectins with Navinci’s proprietary in situ Proximity Ligation Assay (isPLA). This provides a simple approach to understand glycan-protein proximity with a spatial context.
Glycan screening kit
Glysite Scout Glycan Screening Kits are immunofluorescence kits designed to enhance the visualization of glycan expression in tissue samples. These kits feature a diverse panel of glycan binders (lectins) for detecting major glycan motifs such as mannose, galactose, and complex N-glycans. They are validated for use on human and mouse tissues, including FFPE samples, across various tissue types like lung, colon, kidney, and more.
Lectin screening kits
Lectin screening kits are panels of lectins or lectin conjugates selected to offer a variety of sugar binding specificities. The smaller volume unit sizes in these kits are of the same high quality as individually offered lectin units.
Lectins
Lectins, such as Concanavalin A (Con A) and wheat germ agglutinin (WGA), are specialized proteins that bind to carbohydrates, making them essential tools for selectively staining cell surfaces and organelles. These robust proteins can withstand processes like fixation and permeabilization, ensuring effective staining of both live cells and internal structures. Whether you're studying blood vessels, endothelial cells, or specific cellular markers, our range of lectin products offers unparalleled precision and versatility.
Glycoprotein elution solutions
Glycoproteins are frequently isolated and purified from protein mixtures using columns of agarose-bound lectins. Glycoprotein Elution Solutions maximize the yield of eluted glycoproteins and preserve the activity of the agarose-bound lectins.
BROCHURES & DOWNLOADS
Lectins Application and Resource Guide
Explore how lectins can help your research with tips, workflows, publications and more.
Guidebook: Glycobiology and Cancer
Learn more about how Vector reagents support investigation of complex glycans in cancer research.
Guidebook: Glycobiology 101
Explore the world of glycobiology, including implications in health and disease and applications of lectins.
Lectin Infographic
Explore how lectins serve as powerful research tools for a variety of applications.
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