New England Biolabs
PCR polymerases
The choice of polymerase affects both the efficiency and accuracy of PCR experiments. We offer polymerases suited to different requirements.

OneTaq and OneTaq Hot Start DNA polymerases
OneTaq and OneTaq Hot Start DNA Polymerases combine Taq and Deep Vent® enzymes for robust, high-fidelity amplification across diverse templates, with hot start aptamer technology for convenient, room-temperature setup and reliable results - even with high GC content.

Q5® high-fidelity DNA polymerase products
Delivers unparalleled accuracy, offering error rates approximately 280 times lower than Taq, while providing robust amplification with minimal optimization and superior performance across a broad range of amplicons, regardless of GC content.

Taq DNA polymerases
Classic Taq DNA Polymerase is an affordable and reliable choice for routine PCR, known for its robustness and ease of use.
We offer a wide range of Taq-based formats to match your workflow, including Taq DNA Polymerase with ThermoPol Buffer, Hot Start Taq DNA Polymerase and convenient 2X Master Mixes (with or without hot start, and Quick-Load for direct gel loading) for standard PCR, as well as a dedicated Multiplex PCR 5X Master Mix for robust, end-point multiplex PCR.

DNA Polymerase Selection Chart
Not sure which DNA polymerase to choose?
Use NEB’s DNA Polymerase Selection Chart to compare performance and find the best fit for your PCR.
