Axol Bioscience
 

We are happy to introduce Axol Bioscience!

Axol Bioscience believes that having more human-relevant disease models will expand scientific knowledge and de-risk drug development. They use human iPSCs to achieve this and have been doing so for over a decade.

They take cells from patient and healthy donors and, using their leading iPSC technology, work with researchers to build physiologically relevant in vitro models. They have a special focus on neurodegenerative diseases, such as Alzheimer’s Disease, as well as cardiotoxicity to promote drug safety.

 

Browse all products from Axol

axoCells™

With over a decade of experience, Axol has developed the manufacturing capabilities to produce high-quality, functional iPSC-derived cells with excellent consistency. Your research can benefit from their quality-focused approach, with a catalog of iPSC-derived neurons, neuroinflammatory cells, muscle cells, and cardiomyocytes manufactured at their ISO 9001:2015-accredited production facility.

axoCells cell types:

  • cortical excitatory neurons
  • striatal neurons
  • cortical inhibitory interneurons
  • sensory neurons
  • motor neurons
  • neuroinflammatory cells (microglia and astrocytes)
  • cardiac cells (atrial and ventricular cardiomyocytes)
  • muscle cells (skeletal myotubes)

Key therapy areas include:

  • Alzheimer's disease
  • Parkinson's disease
  • ALS
  • Huntington's disease
  • Friedreich's ataxia
  • Frontotemporal dementia
axoCells kit codeiPSC-derived cells only DonorDisease Gene/mutation
NEURONS
Cortical excitatory neuronsax5112ax0112Female, 38Alzheimer’s diseasePSEN1 L286V
ax5113ax0113Male, 53Alzheimer’s diseasePSEN1 M146L
ax5114ax0114Female, 31Alzheimer’s diseasePSEN1 A246E
ax5115ax0015Male, newbornHealthy control-
ax5118ax0018Male, 74Healthy control-
Striatal neuronsax3115ax0015Male, newbornHealthy control-
ax3118ax0018Male, 74Healthy control-
Cortical inhibitory 
interneurons
-ax0662Male, 40-50Healthy control-
-ax0667Male, newborn Healthy control-
Sensory neurons-ax0555Male, newbornHealthy control-
ax0157ax0055Male, newbornHealthy control-
Motor neuronsax0183ax0073Male, 62ALS control (asymptomatic) C90RF72 >145 G4C2
ax0184ax0074Female, 64ALS disease C90RF72 >145 G4C2
ax0186ax0076MaleHealthy control-
ax0178ax0078Male, 74Healthy control-
ax0189ax0079FemaleALSTDP436
ax01835ax0735FemaleALSSOD1 Het D109Y (G>T)
NEUROINFLAMMATORY CELLS
Microgliaax0679ax0664Male, 40-50Healthy control-
Astrocytes-ax0704Male, Newborn Healthy control-
PAIN AND SENSATION
Sensory neurons-ax0555Male, NewbornHealthy control-
ax0157ax0055Male, Newborn Healthy control-
CARDIOVASCULAR
Ventricular cardiomyocytesax2500ax2508Male, 74Healthy control-
Atrial cardiomyocytesax2510ax2518Male, 74Healthy control-
OPTHALMOLOGY
Retinal pigment epithelial cellsPCi-RPE_KITPCi-RPE_CAUMale, 5Healthy control-
DERMATOLOGY
SebocytesPCi-SEB_CAU_KITPCi-SEB_CAUMale, 5Healthy control-

Reach out for more information!

 

Johanne Uthus Hermansen

Product specialist

johanne@bionordika.no

Johanne Uthus Hermansen

 

Contact us 

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