Cygnus Technologies
Trust your gene therapy and vaccine development
to the highest quality analytics
The product line from Cygnus Technologies continues to expand to meet your needs as you develop critical cell and gene therapies and vaccines. They know you need to scale up and conduct quality control quickly and efficiently with the highest level of confidence.
- Host cell protein (HCP) ELISA Kits for viral vector and vaccine manufacturing and QC:
HEK293 • Sf9 • BHK • HeLa • A549 • MRC5 • PER.C6® • PG13 • CAP® • Vero • MDCK - Process-Related Impurity ELISA Kits:
EndonucleaseGTP® • BSA • HSA • Human Transferrin • AVIPure® Ligands (AAV2, AAV8 and AAV9) • IsoTag™ Reagents (AAV and LV) - Host Cell DNA Extraction and Human Host Cell DNA Detection and Quantification Kits
- Viral Clearance Kits
HCP ELISA and other process impurity kits:
| HCP ELISA Kits | ||||
|---|---|---|---|---|
| Cell line | Cat.no. | Sensitivity, LOD | Sensitivity, LLOQ | Recommended sample diluent |
| HEK 293 | CYG-F650S | ~0.35 ng/mL | ~2.0 ng/mL | I700 |
| Sf9 | CYG-F1040 | 0.3 ng/mL | ~ 3 ng/mL | I094 |
| HeLa | CYG-F810 | 0.5 ng/mL | 2 ng/mL | I094 |
| Per.C6 | CYG-F1055 | ~1.2 ng/mL | ~5 ng/mL | I028 |
| PG13 | CYG-F995 | ~0.4 ng/mL | ~ 3 ng/mL | I028 |
| Vero | CYG-F975 | ~1.4 ng/mL | ~ 3 ng/mL | I028 |
| BHK | CYG-F510 | 0.4 ng/mL | 1 ng/mL | I028 |
| A549 | CYG-F230 | 0.5 ng/mL | 1.6 ng/mL | F223A |
| MRC5 | CYG-F300 | ~1.8 ng/mL | ~5 ng/mL | I028 |
| CAP | CYG-F820 | ~0.9 ng/ml | ~1,5 ng/ml | I094 |
| Process-Related Impurity ELISA Kits | ||||
|---|---|---|---|---|
| Impurity Type | Cat.no. | Sensitivity, LOD | Sensitivity, LLOQ | Recommended sample diluent |
| Bovine Serum Albumin (BSA) | CYG-F030 | ~125 pg/mL | ~250 pg/mL | F031A |
| Human Serum Albumin (HSA) | CYG-F055 | ~0.15 ng/mL | ~0.28 ng/mL | I028 |
| Bovine Transferrin | CYG-F120 | ~200 pg/mL | ~250 pg/mL | F031A |
| Human Transferrin | CYG-F035N | ~50 pg/mL | ~125 pg/mL | I028 |
| EndonucleaseGTP® | CYG-F960 | ~0.06 ng/mL | ~0.31 ng/mL | I600 |
| Residual Chromatography Resin Leachate ELISA Kits | ||||
|---|---|---|---|---|
| Leachate/Ligand Type | Cat.no. | Sensitivity, LOD | Sensitivity, LLOQ | Recommended sample diluent |
| Avitide AVIPure® - AAV2 | CYG-F1000 | ~0.02 ng/mL | ~0.16 ng/mL | I028 |
| Avitide AVIPure® - AAV9 | CYG-F970 | ~260 pg/mL | 800 pg/mL | I300 |
| Avitide AVIPure® - AAV8 | CYG-F1005 | ~0.06 ng/mL | ~0.5 ng/mL | I028 |
| IsoTag™ AAV Reagent | CYG-F1035 | ~0.08 ng/mL | ~0.16 ng/mL | I028 |
| IsoTag™ LV Reagent | CYG-F1070 | ~0.01 ng/mL | ~0.16 ng/mL | I600 |
| Human Host Cell DNA Kits | ||||
|---|---|---|---|---|
| DNA Kit | Cat.no. | Sensitivity, LOD | Sensitivity, LLOQ | Detection Method |
| Human Host Cell DNA Detection Kit in Tubes | CYG-D160T | NA | 1 pg/µL | PicoGreen® |
| Human Host Cell DNA Detection Kit in Wells | CYG-D160W | NA | 500 fg/µL | PicoGreen® |
| Human AccuRes™ Quantitative DNA Kit | D1165 | 3 fg/μL | 30 fg/μL | Probe-based qPCR |
