Stem cells
Normal and diseased

• Poietics^TM Diabetic Human Adipose Derived Stem Cells (ADSC) are isolated from lipoaspirates collected from adult diabetic type 1 and type 2 donors during surgical liposuction procedures. These cells exhibit very similar phenotypic and functional characteristics to bone marrow-derived mesenchymal stem cells.
• Poietics^TM Human Dental Pulp Stem Cells (DPSC) are isolated from wisdom teeth from adult donors. These cells display highly similar phenotypic and functional characteristics to bone marrow-derived mesenchymal stem cells.
• Poietics^TM Normal Human Adipose Derived Stem Cells (hADSC) are isolated from (non-diabetic) lipoaspirates collected during liposuction procedures in adult donors.
• Poietics^TM Normal Human Bone Marrow Derived Mesenchymal Stem Cells (hMSC) are isolated from normal (non-diabetic) bone marrow in adult donors.

CD34+ CELLS
Lonza ensures the high purity of its CD34+ cells sourced from various origins through meticulous isolation techniques. Bone marrow CD34+ cells are separated from bone marrow mononuclear cells (MNC) using positive immunomagnetic selection, guaranteeing a purity of ≥90%. Similarly, mobilized peripheral blood CD34+ hematopoietic stem and progenitor cells undergo positive selection via an immunomagnetic CD34 microbead labeling system. Lonza's cord blood CD34+ cells, derived from cord blood mononuclear cells (MNCs), also undergo positive immunomagnetic separation, with a guaranteed purity of ≥90% evidenced by CD34+ expressing cells. Additionally, Lonza offers cryopreserved Bone Marrow Mononuclear Cells, obtained through density gradient separation, effectively eliminating erythrocytes and granulocytes to yield a more stable cell product.