Getinge Applikon
Bioreactors and fermentors
Regardless of which bioreactor or fermenter you require, Getinge Applikon can provide a suitable system. From micro-fermenter systems, through benchtop reactors in glass and steel, up to pilot and manufacturing vessels of thousands of litres.
Regardless of which bioreactor or fermenter you require, Getinge Applikon can provide a suitable system. From micro-fermenter systems, through benchtop reactors in glass and steel, up to pilot and manufacturing vessels of thousands of litres. We provide bioreactor systems for all applications, from high-throughput screening, process optimization, studies, education, scale-up or manufacturing. Applikon systems are available for all sectors: Academical and medical research, biotechnological process development, and industry.
Getinge Applikon are known for their excellent quality and good products. As your local distributor we will cooperate with you to ensure you get a solution that fit your needs. Following the installation of your reactor system, we will be ready to provide technical and application support.
Contact us to receive a catalogue of Getinge Applikon bioreactors and solutions.
Bioreactors
Applikon bioreactors are available in many designs:
- Micro-fermenter system, cartridge with working volume 1 mL to 5 mL
- Borosilicate, reactor vessel with total volume from 250 mL to 20 L
- Single use reactors, reactor vessel with total volume from 500 mL to 3 L
- Pilot steel, total volume from 15 L to 270 L
- Production steel, total volume up to 5.000 L
Applikon bioreactor systems are customised to fit your requirements. The systems are normally configured for cell culture or microbiological culture (yeast and bacteria), and can be as specialized or generic as desired. Applikon systems are also very well suited for scale-up, which makes it easy to transfer processes from screening via optimization to production.
Control systems
Applikon bioprocess controllers combine reliable and accurate control of all parameters with user friendly solutions and easy operation. The controller is normally configured for cell culture or microbiological culture (yeast and bacteria), and controls all bioprocess parameters: pH, temperature, dissolved oxygen, agitation, antifoam and liquid level. The controllers have connections for digital and analogue sensors and systems, for example balances or external sensors with a 4-20 mA signal may be used. An extended I/O module can be included for increased flexibility.
Depending on the system, it can be operated locally on the instrument, through web browser on computer or tablet, or with dedicated software. For industrial applications we provide software compatible with Emerson DetaV, Allen Bradley and Siemens PLC.
Software
Applikon provides software from basic data logging and storage up to complete, automated control systems for industry:
- Lucullus is a cost-efficient and scalable software package that can be used for most applications. The basic version, which is included with all Applikon systems, allows logging, storage and export of data. More advanced versions can be used for automating the process control, data analysis, report generation, and management of media production and reactor allocation. All data is stored in an Oracle database.
- V-Control is DeltaV-based, suitable for those already using this platform or desiring to do so. It provides full process control, automation, and data management from discovery to production. Using DeltaV in both process development and manufacture enables fast and problem free scale-up, with reduced time requirements and cost as a result.
Sensors and bioprocess analysis
Reliable sensors are required for full control of a bioreactor system. Applikon provides a range of options:
- AppliSens sensors - for pH, dissolved oxygen and RedOx potential
- Temperature sensor - Pt100
- Biomass sensor - for continuous monitoring
- Off-gas analysis - Cartridge-based system for analysing gas levels in reactor exhaust: Oxygen, carbon dioxide, methane, hydrogen and ethanol.
Complete systems ready-to-use - Biobundle
To make the process of getting started with your fermenter as easy as possible, Applikon provides many of its systems as a complete bundle solution – the Biobundle. A Biobundle is configured by you in cooperation with a product specialist, based on what the system is intended to be used for. From this a default configuration is selected, to which additional options and functionality can be added as desired. A Biobundle is supplied complete with software, spare parts, and enough consumables to assemble and get started ‘right out of the box’.
Training
Depending on your level of experience, we offer appropriate user training:
- Guidance and application support for those already experienced with Applikon systems
- Introduction to Applikon equipment for those already experienced with bioreactors, but unfamiliar with Applikon systems
- Full training covering both equipment and process, for those with no previous bioreactor experience
The training can be conducted at your location, at the Applikon training centre in the Netherlands, or online.
Reach out for more information!
